If you step off a cliff you are going to go splat. Gravity is the principle that will suck you down to your death. Gravity is also the principle that keeps us all from floating off into space.
No matter what area of business you are in, principles exist that will lead to success or failure depending on how you behave. So figure out the best practices for your industry and make principles work for you.
What principles guide your profession? Are these principles working for you or against you?